Antiretroviral therapy blocks natural selection on protective and disease-susceptible HLA-B alleles in HIV-1 infection

N.G. Herbert, G. Cromhout, N. Bengu, R. Fillis, S. Kannie, J. van Lobenstein, K. Chinniah, C. Kapongo, R. Bhoola, M. Krishna, N. Mchunu, T. Arumugam, K. Dong, S. Gupta, C. Brander, M. Carrington, T. Ndung’u, V. Ramsuran, B.S. Penman, & P.J.R. Goulder, Antiretroviral therapy blocks natural selection on protective and disease-susceptible HLA-B alleles in HIV-1 infection, Proc. Natl. Acad. Sci. U.S.A. 123 (19) e2502683123, https://doi.org/10.1073/pnas.2502683123 (2026).