PAVE is the first global Martin Delaney Collaboratory focused on HIV remission and cure therapies in children
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Estimated 1.5 million children under 15 live with HIV/AIDS
130,000 new pediatric HIV infections annually
Estimated only 57% of pediatric patients are being treated

Paving the way to remission and cure

The PAVE Collaboratory aims to identify and harness the distinct immunovirological features of HIV reservoirs in children and adolescents through access to unique cohorts and biospecimens. Working with pediatric nonhuman primate models, PAVE team members will conduct preclinical safety and effectiveness research studies of novel treatments. The collaboratory will also focus on developing procedures, tools and techniques, including imaging, specifically for infants, children and adolescents.

PAVE Collaboratory is part of the
Martin Delaney Collaboratories

The purpose of the collaboratory is to foster dynamic, multidisciplinary collaborations between basic, applied, and clinical researchers studying HIV persistence and developing potential curative strategies.

PAVE academic institutions work with community, industry and NIH partners to advance pediatric HIV research.

PAVE diagram
18 research institutions, biobanks and cohorts are working together to cure pediatric HIV/AIDS
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University of South Florida
Zachary (James) Porterfield, MD
Tampa, Florida
USA
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Boston Children's Hospital (PVP)  
Ofer Levy, MD, PhD
Boston, Massachusetts
USA
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Massachusetts General Hospital/ Ragon Institute
Mathias Lichterfeld, MD, PhD
Roger Shapiro, MD
Ryan McNamara, PhD
Boston, Massachusetts
USA
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University of Massachusetts
Katherine Luzuriaga, MD
Worcester, Massachusetts
USA
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Weill Cornell Medical College
Sallie Permar, MD, PhD
New York, New York
USA
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National Institutes of Health
Mario Roederer, PhD
Rick Koup, MD
Joe Cassazaa, MD
Bethesda, Maryland
USA
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Johns Hopkins University School of Medicine
Deborah Persaud, MD
Baltimore, Maryland
USA
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Emory University
Ann Chahroudi, PhD, MD
Atlanta, Georgia
USA
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Stellenbosch University
Mark Cotton, MD, PhD
Barbara Laughton, MD
Gert VanZyl, PhD
Richard Glashoff, PhD
Stellenbosch, South Africa
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Ospedale Pediatrico Bambino Gesù
Paolo Palma, MD, PhD
Nicola Cotugno, MD, PhD
Rome, Italy
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Oxford University
Philip Goulder, MA, FRCPCH
Dphil, FMedSci 
Oxford, United Kingdom
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University of Miami
Savita Pahwa, MD
Lesley deArmas, PhD
Miami, Florida
USA
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UF Scripps Biomedical Research
Mauricio Martins, PhD
Michael Farzan, PhD
Jupiter, Florida
USA
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African Health Research Institute
Henrik Kløverpris, PhD
Durban, South Africa
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University of the Witwatersrand
Avy Violari, MD
Caroline Tiemessen, PhD
Johannesburg, South Africa

Thank you to our NIH Partners

Grant Number: UM1AI164566

NIAID NIDA NIMH NICHD